PUBLICATIONS

Computer vision to predict cell seeding coverage in re-endothelialized mouse lungs

Joshua Paciocco 1, Ahmed Hasan 1, Jason Chan 1, Daisuke Taniguchi 2, Cristina Amon 1 3, Golnaz Karoubi 1 2 4, Aimy Bazylak 5
Orthotopic transplantation of the bioengineered lung using a mouse-scale perfusion-based bioreactor and human primary endothelial cells

Fumiko Tomiyama 1, Takaya Suzuki 2 3, Tatsuaki Watanabe 1, Jun Miyanaga 4, Anna Suzuki 4, Takayasu Ito 1, Sho Murai 1, Yuyo Suzuki 1, Hiromichi Niikawa 1, Hisashi Oishi 1, Hirotsugu Notsuda 1, Yui Watanabe 1, Takashi Hirama 1, Ken Onodera 1, Takeo Togo 1, Masafumi Noda 1, Thomas K Waddell 5 6, Golnaz Karoubi 5 7, Yoshinori Okada 1
Bioengineering of vascularized porcine flaps using perfusion-recellularization

Michael S Xu 1, Andrew D'Elia 1, Nina Hadzimustafic 1, Aisha Adil 1, Golnaz Karoubi 1, Thomas K Waddell 1 2, Siba Haykal 3 4
Mesenchymal cells support the early retention of primary alveolar type 2 cells on acellular mouse lung scaffolds

Daisuke Taniguchi 1 2, Mohammadali Ahmadipour 1 3, Anthony L Eiliazadeh 1, Pascal Duchesneau 1, Takeshi Nagayasu 2, Siba Haykal 1 3 4, Golnaz Karoubi 1 5 6, Thomas K Waddell
Effects of Warm Versus Cold Ischemic Donor Lung Preservation on the Underlying Mechanisms of Injuries During Ischemia and Reperfusion

Ilker Iskender 1 2, Marcelo Cypel 1 2 3, Tereza Martinu 1, Manyin Chen 1, Jin Sakamoto 1, Hyunhee Kim 1, Keke Yu 1, Huiqing Lin 1, Zehong Guan 1, Kohei Hashimoto 1, Thomas K Waddell 1 2 3, Mingyao Liu 1 2 3, Shaf Keshavjee 1 2 3
GDF11 secreting cell transplant efficiently ameliorates age-related pulmonary fibrosis

Li Guo 1, Pascal Duchesneau 2, Eric D Jong 1, Evan Sawula 1, Chengjin Li 1, Thomas K Waddell 3, Andras Nagy 4
North American expert consensus on the clinical role of ex vivo lung perfusion (EVLP) with acellular perfusate

Matthew Bacchetta 1, Christian A Bermudez 2, Ankit Bharat 3, A Whitney Brown 4, Marie M Budev 5, Marcelo Cypel 6, Caitlin T Demarest 7, Daniel F Dilling 8, Bartley P Griffith 9, John C Haney 10, Shaf Keshavjee 6, Zachary N Kon 11, Tiago N Machuca 12, Jorge M Mallea 13, Si M Pham 11, Thomas K Waddell 6, Bryan A Whitson 14, Kenneth R McCurry 15
YAP1::TFE3 fusion in a case of malignant TFE3-rearranged PEComa of the lung: expanding the spectrum of pulmonary PEComa-like mesenchymal neoplasms

Ying-Han R Hsu 1 2, Shamini Selvarajah 3 4, Prodipto Pal 3 4, Thomas K Waddell 5 6
Analysis of outcomes in resected early-stage NSCLC with rare targetable driver mutations

Nadia Ghazali 1 2, Jamie Feng 1 2, Katrina Hueniken 3, Khaleeq Khan 4, Karmugi Balaratnam 4, Thomas K Waddell 5 2, Kazuhiro Yasufuku 5 2, Andrew Pierre 5 2, Laura Donahoe 5 2, Elliot Wakeam 5 2, Marcelo Cypel 5 2, Jonathan Yeung 5 2, Shaf Keshavjee 5 2, Marc de Perrot 5 2, Natasha B Leighl 1 2, Geoffrey Liu 1 2, Penelope A Bradbury 1 2, Adrian Sacher 1 2, Lawson Eng 1 2, Tracy Stockley 6 7, Ming Sound Tsao 8 2, Frances A Shepherd 8 2
The effect of decellularization of tracheal allografts on leukocyte infiltration and of recellularization on regulatory T cell recruitment

Siba Haykal 1 , Yingzhe Zhou , Paula Marc us , Michael Sa lna , Tiago Machu ca , Stefan O P Hofer , Thomas K Wadde ll 1, John P Solea s, Michael Salna, Stefan O P Hofer, Thomas K Waddell
Bioreactor-based de-epithelialization of long-segment tracheal grafts

Marin-Araujo, A.E., Haykal, S., & Karoubi, G. (2022). Methods in Molecular Biology, 2436: 167–182. https://doi.org/10.1007/7651_2021_431
De-epithelialization of porcine tracheal allografts as an approach for tracheal tissue engineering

Fabio G Aoki 1 2, Ratna Varma 1 3, Alba E Marin-Araujo 3, Hankyu Lee 4, John P Soleas 1 3, Alexander H Li 1, Kayla Soon 1, David Romero 4, Henrique T Moriya 2, Siba Haykal 1, Cristina Amon 3 4, Thomas K Waddell 5 6, Golnaz Karoubi 7 8
Procurement and perfusion-decellularization of porcine vascularized flaps in a customized perfusion bioreactor

Xu, M.S., Karoubi, G., Waddell, T.K., & Haykal, S. (2022). Journal of Visualized Experiments, (186), e64068. http://doi.org/10.3791/64068
Computational fluid dynamics for enhanced tracheal bioreactor design and long-segment graft recellularization

Lee, H., Marin-Araujo, A. E., Aoki, F. G., Haykal, S., Waddell, T. K., Amon, C. H., Romero, D. A., & Karoubi, G. (2021). Scientific reports, 11(1), 1187. https://doi.org/10.1038/s41598-020-80841-w
De-epithelialization of porcine tracheal allografts as an approach for tracheal tissue engineering

Aoki, F. G., Varma, R., Marin-Araujo, A. E., Lee, H., Soleas, J. P., Li, A. H., Soon, K., Romero, D., Moriya, H. T., Haykal, S., Amon, C., Waddell, T. K., & Karoubi, G. (2019). Scientific reports, 9(1), 12034. https://doi.org/10.1038/s41598-019-48450-4
Short-Term Preclinical Application of Functional Human Induced Pluripotent Stem Cell-Derived Airway Epithelial Patches

Varma, R., Marin-Araujo, A. E., Rostami, S., Waddell, T. K., Karoubi, G., & Haykal, S. (2021). Advanced healthcare materials, 10(21), e2100957. https://doi.org/10.1002/adhm.202100957
Negative Pressure Cell Delivery Augments Recellularization of Decellularized Lungs

Ahmadipour, M., Duchesneau, P., Taniguchi, D., Waddell, T. K., & Karoubi, G. (2021). Part C, Methods, 27(1), 1–11. https://doi.org/10.1089/ten.TEC.2020.0251
Evaluation of Early Markers of Ischemiareperfusion Injury and Preservation Solutions in a Modified Hindlimb Model of Vascularized Composite Allotransplantation

Rostami, Xu, M., Datta, S., & Haykal, S. (2022). Transplantation Direct, 8(1), e1251–e1251. https://doi.org/10.1097/TXD.000000000000125
Generation of Induced Progenitor-like Cells from Mature Epithelial Cells Using Interrupted Reprogramming

Guo, L., Karoubi, G., Duchesneau, P., Shutova, M. V., Sung, H. K., Tonge, P., Bear, C., Rogers, I., Nagy, A., & Waddell, T. K. (2017). Stem cell reports, 9(6), 1780–1795. https://doi.org/10.1016/j.stemcr.2017.10.022
In silico model development and optimization of in vitro lung cell population growth

Amirmahdi Mostofinejad 1, David A Romero 1, Dana Brinson 2, Alba E Marin-Araujo 2 3, Aimy Bazylak 1, Thomas K Waddell 2 3, Siba Haykal 2 4, Golnaz Karoubi 2 3, Cristina H Amon 1 2. https://pmc.ncbi.nlm.nih.gov/articles/PMC11095723/.
Bioengineering of vascularized porcine flaps using perfusion-recellularization

Xu, M.S., D'Elia, A., Hadzimustafic, N., Adil, A., Karoubi, G., Waddell, T.K., Haykal, S. (2024). Scientific Reports, 14(1):7590. http://doi.org/10.1038/s41598-024-58095-7
Guided self-assembly of ES-derived lung progenitors into biomimetic tube structures that impact cell differentiation

Soleas, J.P., Huang, L., D’Arcangelo, E., Nostro, M.C., Waddell, T.K., McGuigan, A.P., & Karoubi, G. (2021). Bioengineering, 8, 209. https://doi.org/10.3390/bioengineering8120209

Read More of Dr. Haykal's Work Here

Read More of Dr. Karoubi's Work Here

Read More of Dr. Waddell's Work Here

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